{"id":704,"date":"2026-04-09T11:09:16","date_gmt":"2026-04-09T09:09:16","guid":{"rendered":"https:\/\/wellfedhippo.com\/?p=704"},"modified":"2026-05-07T14:03:27","modified_gmt":"2026-05-07T11:03:27","slug":"%d0%bc%d0%b5%d1%82%d0%b8%d0%bb%d1%81%d1%83%d0%bb%d1%8c%d1%84%d0%be%d0%bd%d0%b8%d0%bb%d0%bc%d0%b5%d1%82%d0%b0%d0%bd-msm-%d0%be%d0%b1%d0%b7%d0%be%d1%80-%d0%b8-%d0%bf%d1%80%d0%b0%d0%ba%d1%82%d0%b8","status":"publish","type":"post","link":"https:\/\/www.wellfedhippo.com\/?p=704","title":{"rendered":"\u0421\u0435\u0440\u0430: \u041c\u0435\u0442\u0438\u043b\u0441\u0443\u043b\u044c\u0444\u043e\u043d\u0438\u043b\u043c\u0435\u0442\u0430\u043d (MSM) – \u043e\u0431\u0437\u043e\u0440 \u0438 \u043f\u0440\u0430\u043a\u0442\u0438\u043a\u0430 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u044f"},"content":{"rendered":"

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\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c\u044b \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f MSM \u0441\u0432\u044f\u0437\u0430\u043d\u044b \u0441 \u0435\u0433\u043e \u0441\u043f\u043e\u0441\u043e\u0431\u043d\u043e\u0441\u0442\u044c\u044e \u0432\u043e\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u043e\u0432\u0430\u0442\u044c \u043d\u0430 \u043a\u043b\u044e\u0447\u0435\u0432\u044b\u0435 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u044b\u0435 \u0441\u0438\u0433\u043d\u0430\u043b\u044c\u043d\u044b\u0435 \u043f\u0443\u0442\u0438, \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0443\u044e\u0449\u0438\u0435 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u0438 \u043e\u043a\u0438\u0441\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0439 \u0441\u0442\u0440\u0435\u0441\u0441<\/strong>. \u041e\u0434\u043d\u0438\u043c \u0438\u0437 \u0446\u0435\u043d\u0442\u0440\u0430\u043b\u044c\u043d\u044b\u0445 \u043c\u0435\u0445\u0430\u043d\u0438\u0437\u043c\u043e\u0432 \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0438\u043d\u0433\u0438\u0431\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 \u0442\u0440\u0430\u043d\u0441\u043a\u0440\u0438\u043f\u0446\u0438\u043e\u043d\u043d\u043e\u0433\u043e \u0444\u0430\u043a\u0442\u043e\u0440\u0430 NF-\u03baB, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u0438\u0433\u0440\u0430\u0435\u0442 \u043a\u043b\u044e\u0447\u0435\u0432\u0443\u044e \u0440\u043e\u043b\u044c \u0432 \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u0438 \u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0433\u0435\u043d\u043e\u0432. \u041f\u043e\u0434\u0430\u0432\u043b\u0435\u043d\u0438\u0435 NF-\u03baB \u043f\u0440\u0438\u0432\u043e\u0434\u0438\u0442 \u043a \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u044e \u0441\u0438\u043d\u0442\u0435\u0437\u0430 \u043f\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0446\u0438\u0442\u043e\u043a\u0438\u043d\u043e\u0432, \u0432\u043a\u043b\u044e\u0447\u0430\u044f \u0438\u043d\u0442\u0435\u0440\u043b\u0435\u0439\u043a\u0438\u043d\u044b IL-1 \u0438 IL-6, \u0430 \u0442\u0430\u043a\u0436\u0435 \u0444\u0430\u043a\u0442\u043e\u0440 \u043d\u0435\u043a\u0440\u043e\u0437\u0430 \u043e\u043f\u0443\u0445\u043e\u043b\u0438 TNF-\u03b1.<\/p>\n

\u0414\u043e\u043f\u043e\u043b\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e MSM \u0441\u043d\u0438\u0436\u0430\u0435\u0442 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u0444\u0435\u0440\u043c\u0435\u043d\u0442\u043e\u0432 iNOS \u0438 COX-2, \u0447\u0442\u043e \u043f\u0440\u0438\u0432\u043e\u0434\u0438\u0442 \u043a \u0443\u043c\u0435\u043d\u044c\u0448\u0435\u043d\u0438\u044e \u043f\u0440\u043e\u0434\u0443\u043a\u0446\u0438\u0438 \u043e\u043a\u0441\u0438\u0434\u0430 \u0430\u0437\u043e\u0442\u0430 \u0438 \u043f\u0440\u043e\u0441\u0442\u0430\u043d\u043e\u0438\u0434\u043e\u0432, \u0443\u0447\u0430\u0441\u0442\u0432\u0443\u044e\u0449\u0438\u0445 \u0432 \u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0440\u0435\u0430\u043a\u0446\u0438\u044f\u0445. \u0422\u0430\u043a\u0436\u0435 \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0435\u0442\u0441\u044f \u043f\u043e\u0434\u0430\u0432\u043b\u0435\u043d\u0438\u0435 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u0438\u043d\u0444\u043b\u0430\u043c\u043c\u0430\u0441\u043e\u043c\u044b NLRP3, \u0447\u0442\u043e \u0441\u043d\u0438\u0436\u0430\u0435\u0442 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u044b\u0439 \u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0439 \u043e\u0442\u0432\u0435\u0442. \u042d\u0442\u0438 \u044d\u0444\u0444\u0435\u043a\u0442\u044b \u0440\u0435\u0430\u043b\u0438\u0437\u0443\u044e\u0442\u0441\u044f \u043a\u0430\u043a \u043d\u0430 \u0443\u0440\u043e\u0432\u043d\u0435 \u0442\u0440\u0430\u043d\u0441\u043a\u0440\u0438\u043f\u0446\u0438\u0438 \u0433\u0435\u043d\u043e\u0432, \u0442\u0430\u043a \u0438 \u043d\u0430 \u0441\u0443\u0431\u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u043c \u0443\u0440\u043e\u0432\u043d\u0435.<\/p>\n

\u0410\u043d\u0442\u0438\u043e\u043a\u0441\u0438\u0434\u0430\u043d\u0442\u043d\u044b\u0435 \u0441\u0432\u043e\u0439\u0441\u0442\u0432\u0430 MSM \u043f\u0440\u043e\u044f\u0432\u043b\u044f\u044e\u0442\u0441\u044f \u0447\u0435\u0440\u0435\u0437 \u0440\u0435\u0433\u0443\u043b\u044f\u0446\u0438\u044e \u043d\u0435\u0441\u043a\u043e\u043b\u044c\u043a\u0438\u0445 \u0442\u0440\u0430\u043d\u0441\u043a\u0440\u0438\u043f\u0446\u0438\u043e\u043d\u043d\u044b\u0445 \u0444\u0430\u043a\u0442\u043e\u0440\u043e\u0432, \u0432\u043a\u043b\u044e\u0447\u0430\u044f NF-\u03baB, STAT, p53 \u0438 Nrf2. \u041f\u043e\u0434 \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435\u043c MSM \u0443\u043c\u0435\u043d\u044c\u0448\u0430\u0435\u0442\u0441\u044f \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u0435 \u0430\u043a\u0442\u0438\u0432\u043d\u044b\u0445 \u0444\u043e\u0440\u043c \u043a\u0438\u0441\u043b\u043e\u0440\u043e\u0434\u0430, \u0430 \u0442\u0430\u043a\u0436\u0435 \u0443\u0441\u0438\u043b\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u044f \u0430\u043d\u0442\u0438\u043e\u043a\u0441\u0438\u0434\u0430\u043d\u0442\u043d\u044b\u0445 \u0444\u0435\u0440\u043c\u0435\u043d\u0442\u043e\u0432, \u0442\u0430\u043a\u0438\u0445 \u043a\u0430\u043a \u0441\u0443\u043f\u0435\u0440\u043e\u043a\u0441\u0438\u0434\u0434\u0438\u0441\u043c\u0443\u0442\u0430\u0437\u0430, \u043a\u0430\u0442\u0430\u043b\u0430\u0437\u0430 \u0438 \u0433\u043b\u0443\u0442\u0430\u0442\u0438\u043e\u043d\u043f\u0435\u0440\u043e\u043a\u0441\u0438\u0434\u0430\u0437\u0430. \u042d\u0442\u043e \u0441\u043f\u043e\u0441\u043e\u0431\u0441\u0442\u0432\u0443\u0435\u0442 \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u044e \u0431\u0430\u043b\u0430\u043d\u0441\u0430 \u043c\u0435\u0436\u0434\u0443 \u043e\u043a\u0438\u0441\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u043c\u0438 \u0438 \u0430\u043d\u0442\u0438\u043e\u043a\u0441\u0438\u0434\u0430\u043d\u0442\u043d\u044b\u043c\u0438 \u043f\u0440\u043e\u0446\u0435\u0441\u0441\u0430\u043c\u0438 \u0432 \u043a\u043b\u0435\u0442\u043a\u0435.<\/p>\n

\u0418\u043c\u043c\u0443\u043d\u043e\u043c\u043e\u0434\u0443\u043b\u0438\u0440\u0443\u044e\u0449\u0435\u0435 \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435 MSM \u043e\u0431\u0443\u0441\u043b\u043e\u0432\u043b\u0435\u043d\u043e \u0435\u0433\u043e \u0441\u043f\u043e\u0441\u043e\u0431\u043d\u043e\u0441\u0442\u044c\u044e \u0432\u043b\u0438\u044f\u0442\u044c \u043d\u0430 \u0432\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435 \u043c\u0435\u0436\u0434\u0443 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435\u043c \u0438 \u043e\u043a\u0438\u0441\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u043c \u0441\u0442\u0440\u0435\u0441\u0441\u043e\u043c. \u041e\u043d \u0441\u043d\u0438\u0436\u0430\u0435\u0442 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u043f\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u043c\u0435\u0434\u0438\u0430\u0442\u043e\u0440\u043e\u0432 \u0438 \u0441\u043f\u043e\u0441\u043e\u0431\u0441\u0442\u0432\u0443\u0435\u0442 \u0441\u043e\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u044e \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0439 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u0438\u043c\u043c\u0443\u043d\u043d\u044b\u0445 \u043a\u043b\u0435\u0442\u043e\u043a \u043f\u0440\u0438 \u0441\u0442\u0440\u0435\u0441\u0441\u043e\u0432\u044b\u0445 \u0432\u043e\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f\u0445<\/strong>. \u0422\u0430\u043a\u0436\u0435 \u043e\u0442\u043c\u0435\u0447\u0430\u044e\u0442\u0441\u044f \u044d\u0444\u0444\u0435\u043a\u0442\u044b, \u0441\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0435 \u0441 \u0440\u0435\u0433\u0443\u043b\u044f\u0446\u0438\u0435\u0439 \u0430\u043f\u043e\u043f\u0442\u043e\u0437\u0430 \u0438 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u0433\u043e \u0446\u0438\u043a\u043b\u0430, \u0447\u0442\u043e \u043c\u043e\u0436\u0435\u0442 \u0438\u043c\u0435\u0442\u044c \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u0432 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u044b\u0445 \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f\u0445.<\/p>\n

MSM \u0440\u0430\u0441\u0441\u043c\u0430\u0442\u0440\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u043a\u0430\u043a \u0438\u0441\u0442\u043e\u0447\u043d\u0438\u043a \u0441\u0435\u0440\u044b \u0434\u043b\u044f \u0441\u0438\u043d\u0442\u0435\u0437\u0430 \u0441\u0435\u0440\u043e\u0441\u043e\u0434\u0435\u0440\u0436\u0430\u0449\u0438\u0445 \u0430\u043c\u0438\u043d\u043e\u043a\u0438\u0441\u043b\u043e\u0442, \u0442\u0430\u043a\u0438\u0445 \u043a\u0430\u043a \u043c\u0435\u0442\u0438\u043e\u043d\u0438\u043d \u0438 \u0446\u0438\u0441\u0442\u0435\u0438\u043d. \u041e\u0434\u043d\u0430\u043a\u043e \u0443\u0447\u0430\u0441\u0442\u0438\u0435 MSM \u0432 \u044d\u0442\u0438\u0445 \u043f\u0440\u043e\u0446\u0435\u0441\u0441\u0430\u0445 \u0437\u0430\u0432\u0438\u0441\u0438\u0442 \u043e\u0442 \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u044b \u0438 \u0442\u0440\u0435\u0431\u0443\u0435\u0442 \u0434\u0430\u043b\u044c\u043d\u0435\u0439\u0448\u0435\u0433\u043e \u0438\u0437\u0443\u0447\u0435\u043d\u0438\u044f. \u041d\u0430 \u0434\u0430\u043d\u043d\u044b\u0439 \u043c\u043e\u043c\u0435\u043d\u0442 \u043e\u0442\u0441\u0443\u0442\u0441\u0442\u0432\u0443\u044e\u0442 \u0443\u0431\u0435\u0434\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435 \u0434\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u0430 \u0435\u0433\u043e \u0440\u043e\u043b\u0438 \u043a\u0430\u043a \u0434\u043e\u043d\u043e\u0440\u0430 \u043c\u0435\u0442\u0438\u043b\u044c\u043d\u044b\u0445 \u0433\u0440\u0443\u043f\u043f \u0438\u043b\u0438 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u0430 \u043c\u0435\u0442\u0438\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u0414\u041d\u041a<\/strong>.<\/p>\n

\u041d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u0438\u0437\u0443\u0447\u0435\u043d\u043d\u0430\u044f \u043e\u0431\u043b\u0430\u0441\u0442\u044c \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u044f MSM \u0441\u0432\u044f\u0437\u0430\u043d\u0430 \u0441 \u043b\u0435\u0447\u0435\u043d\u0438\u0435\u043c \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u0441\u0443\u0441\u0442\u0430\u0432\u043e\u0432. \u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u0443\u044e\u0442 \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 \u0431\u043e\u043b\u0438, \u0443\u043c\u0435\u043d\u044c\u0448\u0435\u043d\u0438\u0435 \u0441\u043a\u043e\u0432\u0430\u043d\u043d\u043e\u0441\u0442\u0438 \u0438 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u0441\u0443\u0441\u0442\u0430\u0432\u043e\u0432 \u043f\u0440\u0438 \u043e\u0441\u0442\u0435\u043e\u0430\u0440\u0442\u0440\u0438\u0442\u0435. \u042d\u0442\u0438 \u044d\u0444\u0444\u0435\u043a\u0442\u044b \u043f\u043e\u0434\u0442\u0432\u0435\u0440\u0436\u0434\u0430\u044e\u0442\u0441\u044f \u043a\u0430\u043a \u0441\u0443\u0431\u044a\u0435\u043a\u0442\u0438\u0432\u043d\u044b\u043c\u0438 \u0448\u043a\u0430\u043b\u0430\u043c\u0438 \u043e\u0446\u0435\u043d\u043a\u0438 \u0431\u043e\u043b\u0438, \u0442\u0430\u043a \u0438 \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u043c\u0438 \u0442\u0435\u0441\u0442\u0430\u043c\u0438. \u041f\u0440\u0438 \u043a\u043e\u043c\u0431\u0438\u043d\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0438 MSM \u0441 \u0434\u0440\u0443\u0433\u0438\u043c\u0438 \u0432\u0435\u0449\u0435\u0441\u0442\u0432\u0430\u043c\u0438, \u0442\u0430\u043a\u0438\u043c\u0438 \u043a\u0430\u043a \u0433\u043b\u044e\u043a\u043e\u0437\u0430\u043c\u0438\u043d \u0438 \u0445\u043e\u043d\u0434\u0440\u043e\u0438\u0442\u0438\u043d, \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0435\u0442\u0441\u044f \u0443\u0441\u0438\u043b\u0435\u043d\u0438\u0435 \u0442\u0435\u0440\u0430\u043f\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u044d\u0444\u0444\u0435\u043a\u0442\u0430.<\/strong><\/p>\n

MSM \u043e\u043a\u0430\u0437\u044b\u0432\u0430\u0435\u0442 \u0437\u0430\u0449\u0438\u0442\u043d\u043e\u0435 \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435 \u043d\u0430 \u0445\u0440\u044f\u0449\u0435\u0432\u0443\u044e \u0442\u043a\u0430\u043d\u044c, \u0441\u043d\u0438\u0436\u0430\u044f \u0440\u0430\u0437\u0440\u0443\u0448\u0435\u043d\u0438\u0435 \u0432\u043d\u0435\u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u0433\u043e \u043c\u0430\u0442\u0440\u0438\u043a\u0441\u0430 \u0438 \u043f\u043e\u0434\u0430\u0432\u043b\u044f\u044f \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u043f\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0446\u0438\u0442\u043e\u043a\u0438\u043d\u043e\u0432. \u042d\u0442\u043e \u0441\u043f\u043e\u0441\u043e\u0431\u0441\u0442\u0432\u0443\u0435\u0442 \u0437\u0430\u043c\u0435\u0434\u043b\u0435\u043d\u0438\u044e \u0434\u0435\u0433\u0435\u043d\u0435\u0440\u0430\u0442\u0438\u0432\u043d\u044b\u0445 \u043f\u0440\u043e\u0446\u0435\u0441\u0441\u043e\u0432 \u0432 \u0441\u0443\u0441\u0442\u0430\u0432\u0430\u0445<\/strong>.<\/p>\n

\u0414\u043e\u043f\u043e\u043b\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e \u043e\u0442\u043c\u0435\u0447\u0430\u0435\u0442\u0441\u044f \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u0444\u0443\u043d\u043a\u0446\u0438\u0438, \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435 \u043f\u043e\u0434\u0432\u0438\u0436\u043d\u043e\u0441\u0442\u0438 \u0438 \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0431\u043e\u043b\u0438 \u043f\u043e\u0441\u043b\u0435 \u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043d\u0430\u0433\u0440\u0443\u0437\u043e\u043a<\/strong>. MSM \u0441\u043f\u043e\u0441\u043e\u0431\u0435\u043d \u0443\u043c\u0435\u043d\u044c\u0448\u0430\u0442\u044c \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0440\u0435\u0430\u043a\u0446\u0438\u0438, \u0432\u043e\u0437\u043d\u0438\u043a\u0430\u044e\u0449\u0435\u0439 \u043f\u0440\u0438 \u043c\u0438\u043a\u0440\u043e\u0442\u0440\u0430\u0432\u043c\u0430\u0445 \u043c\u044b\u0448\u0446, \u0447\u0442\u043e \u0434\u0435\u043b\u0430\u0435\u0442 \u0435\u0433\u043e \u043f\u043e\u043b\u0435\u0437\u043d\u044b\u043c \u043f\u0440\u0438 \u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u044b\u0445 \u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043d\u0430\u0433\u0440\u0443\u0437\u043a\u0430\u0445.<\/p>\n

\u0412 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f\u0445 \u0442\u0430\u043a\u0436\u0435 \u043f\u043e\u043a\u0430\u0437\u0430\u043d\u043e \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 \u043c\u0430\u0440\u043a\u0435\u0440\u043e\u0432 \u043e\u043a\u0438\u0441\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0433\u043e \u0441\u0442\u0440\u0435\u0441\u0441\u0430, \u0432\u043a\u043b\u044e\u0447\u0430\u044f \u043c\u0430\u043b\u043e\u043d\u043e\u0432\u044b\u0439 \u0434\u0438\u0430\u043b\u044c\u0434\u0435\u0433\u0438\u0434 \u0438 \u043e\u043a\u0438\u0441\u043b\u0435\u043d\u043d\u044b\u0439 \u0433\u043b\u0443\u0442\u0430\u0442\u0438\u043e\u043d, \u0430 \u0442\u0430\u043a\u0436\u0435 \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435 \u043e\u0431\u0449\u0435\u0439 \u0430\u043d\u0442\u0438\u043e\u043a\u0441\u0438\u0434\u0430\u043d\u0442\u043d\u043e\u0439 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438.<\/p>\n

MSM \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u0443\u0435\u0442 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u043f\u0440\u0438 \u0441\u0435\u0437\u043e\u043d\u043d\u044b\u0445 \u0430\u043b\u043b\u0435\u0440\u0433\u0438\u044f\u0445<\/strong>, \u0441\u043d\u0438\u0436\u0430\u044f \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u0440\u0435\u0441\u043f\u0438\u0440\u0430\u0442\u043e\u0440\u043d\u044b\u0445 \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043e\u0432 \u043f\u0440\u0438 \u0440\u0435\u0433\u0443\u043b\u044f\u0440\u043d\u043e\u043c \u043f\u0440\u0438\u0451\u043c\u0435.<\/p>\n

\u0412 \u0434\u0435\u0440\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u043f\u0440\u0430\u043a\u0442\u0438\u043a\u0435 MSM \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u0435\u0442\u0441\u044f \u0434\u043b\u044f \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u044f \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u043a\u043e\u0436\u0438. \u041d\u0430\u0431\u043b\u044e\u0434\u0430\u044e\u0442\u0441\u044f \u044d\u0444\u0444\u0435\u043a\u0442\u044b, \u0432\u043a\u043b\u044e\u0447\u0430\u044e\u0449\u0438\u0435 \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435 \u044d\u043b\u0430\u0441\u0442\u0438\u0447\u043d\u043e\u0441\u0442\u0438, \u0443\u043c\u0435\u043d\u044c\u0448\u0435\u043d\u0438\u0435 \u043c\u043e\u0440\u0449\u0438\u043d \u0438 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u043e\u0431\u0449\u0435\u0433\u043e \u0432\u043d\u0435\u0448\u043d\u0435\u0433\u043e \u0432\u0438\u0434\u0430 \u043a\u043e\u0436\u0438, \u0447\u0442\u043e \u0441\u0432\u044f\u0437\u0430\u043d\u043e \u0441 \u0435\u0433\u043e \u0443\u0447\u0430\u0441\u0442\u0438\u0435\u043c \u0432 \u0441\u0438\u043d\u0442\u0435\u0437\u0435 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u043d\u044b\u0445 \u0431\u0435\u043b\u043a\u043e\u0432.<\/p>\n

\u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f in vitro \u0438 \u043d\u0430 \u0436\u0438\u0432\u043e\u0442\u043d\u044b\u0445 \u043c\u043e\u0434\u0435\u043b\u044f\u0445 \u043f\u043e\u043a\u0430\u0437\u044b\u0432\u0430\u044e\u0442, \u0447\u0442\u043e MSM \u043c\u043e\u0436\u0435\u0442 \u043e\u043a\u0430\u0437\u044b\u0432\u0430\u0442\u044c \u0432\u043b\u0438\u044f\u043d\u0438\u0435 \u043d\u0430 \u043e\u043f\u0443\u0445\u043e\u043b\u0435\u0432\u044b\u0435 \u043a\u043b\u0435\u0442\u043a\u0438, \u043f\u043e\u0434\u0430\u0432\u043b\u044f\u044f \u0438\u0445 \u0440\u043e\u0441\u0442 \u0438 \u043f\u0440\u043e\u043b\u0438\u0444\u0435\u0440\u0430\u0446\u0438\u044e \u0447\u0435\u0440\u0435\u0437 \u0440\u0435\u0433\u0443\u043b\u044f\u0446\u0438\u044e \u0441\u0438\u0433\u043d\u0430\u043b\u044c\u043d\u044b\u0445 \u043f\u0443\u0442\u0435\u0439, \u0432\u043a\u043b\u044e\u0447\u0430\u044f STAT \u0438 p53. \u041e\u0434\u043d\u0430\u043a\u043e \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0443 \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430 \u0432 \u044d\u0442\u043e\u0439 \u043e\u0431\u043b\u0430\u0441\u0442\u0438 \u043e\u0442\u0441\u0443\u0442\u0441\u0442\u0432\u0443\u044e\u0442.<\/strong><\/p>\n

\u0421 \u0442\u043e\u0447\u043a\u0438 \u0437\u0440\u0435\u043d\u0438\u044f \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u0438 MSM \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0437\u0443\u0435\u0442\u0441\u044f \u0432\u044b\u0441\u043e\u043a\u0438\u043c \u0443\u0440\u043e\u0432\u043d\u0435\u043c \u043f\u0435\u0440\u0435\u043d\u043e\u0441\u0438\u043c\u043e\u0441\u0442\u0438. \u0422\u043e\u043a\u0441\u0438\u043a\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u043d\u0430 \u0436\u0438\u0432\u043e\u0442\u043d\u044b\u0445 \u043d\u0435 \u0432\u044b\u044f\u0432\u0438\u043b\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u044b\u0445 \u0440\u0438\u0441\u043a\u043e\u0432 \u0434\u0430\u0436\u0435 \u043f\u0440\u0438 \u0432\u044b\u0441\u043e\u043a\u0438\u0445 \u0434\u043e\u0437\u0430\u0445. \u0412 \u0440\u0435\u0434\u043a\u0438\u0445 \u0441\u043b\u0443\u0447\u0430\u044f\u0445 \u043e\u0442\u043c\u0435\u0447\u0430\u044e\u0442\u0441\u044f \u043b\u0451\u0433\u043a\u0438\u0435 \u0440\u0430\u0437\u0434\u0440\u0430\u0436\u0435\u043d\u0438\u044f \u043a\u043e\u0436\u0438 \u043f\u0440\u0438 \u043d\u0430\u0440\u0443\u0436\u043d\u043e\u043c \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0438.<\/p>\n

\u0422\u0430\u043a\u0438\u043c \u043e\u0431\u0440\u0430\u0437\u043e\u043c, MSM \u043f\u0440\u0435\u0434\u0441\u0442\u0430\u0432\u043b\u044f\u0435\u0442 \u0441\u043e\u0431\u043e\u0439 \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0435 \u0441\u043e\u0435\u0434\u0438\u043d\u0435\u043d\u0438\u0435 \u0441\u0435\u0440\u044b \u0441 \u0448\u0438\u0440\u043e\u043a\u0438\u043c \u0441\u043f\u0435\u043a\u0442\u0440\u043e\u043c \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f, \u0432\u043a\u043b\u044e\u0447\u0430\u044e\u0449\u0438\u043c \u043f\u0440\u043e\u0442\u0438\u0432\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435, \u0430\u043d\u0442\u0438\u043e\u043a\u0441\u0438\u0434\u0430\u043d\u0442\u043d\u044b\u0435 \u0438 \u0438\u043c\u043c\u0443\u043d\u043e\u043c\u043e\u0434\u0443\u043b\u0438\u0440\u0443\u044e\u0449\u0438\u0435 \u044d\u0444\u0444\u0435\u043a\u0442\u044b. \u0415\u0433\u043e \u0444\u0430\u0440\u043c\u0430\u043a\u043e\u043a\u0438\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0441\u0432\u043e\u0439\u0441\u0442\u0432\u0430 \u043e\u0431\u0435\u0441\u043f\u0435\u0447\u0438\u0432\u0430\u044e\u0442 \u0431\u044b\u0441\u0442\u0440\u043e\u0435 \u0432\u0441\u0430\u0441\u044b\u0432\u0430\u043d\u0438\u0435 \u0438 \u0440\u0430\u0432\u043d\u043e\u043c\u0435\u0440\u043d\u043e\u0435 \u0440\u0430\u0441\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0432 \u0442\u043a\u0430\u043d\u044f\u0445, \u0430 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u043d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u043e\u0431\u043e\u0441\u043d\u043e\u0432\u0430\u043d\u043e \u043f\u0440\u0438 \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f\u0445, \u0441\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0445 \u0441 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435\u043c \u0438 \u043e\u043a\u0438\u0441\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u043c \u0441\u0442\u0440\u0435\u0441\u0441\u043e\u043c.<\/p>\n

\u043f\u043e\u043b\u043d\u044b\u0439 \u0442\u0435\u043a\u0441\u0442 – \u0438\u0441\u0442\u043e\u0447\u043d\u0438\u043a:
\nhttps:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5372953\/<\/a><\/p>\n

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